Chemistry 351 Goals for Days 1-8

1) Know the three criteria that must be met for an element to be considered essential.

2) Be able to draw and label key regions of a generic response vs. essential element dosage plot.

3) Know the biological function of group 1 and 2 elements, transition metals with only one oxidation state transition metals that exist in multiple oxidation states.

4) Be able to write the correct electron configuration for both main group and transition metal ions.

5) Be able to describe and give several examples of the inert pair effect.

6) Be able to use Lewis acid-base theory to describe the formation of a coordination compound.

7) Given the formula of the side-chain R groups be able to draw the structure of a tripeptide.

8) Know the four levels of protein structure and be able to give examples of each.

9) Know that in the Pearson Hard-Soft Acid Base concept Lewis acids and bases are characterized as “hard” or “soft”.

10) Be able to classify a species as a hard acid, hard base, soft acid, soft base, borderline acid or borderline base given its electronegativity and position on the periodic table.

11) Know that the HSAB principle can be used to predict the outcome of a chemical reaction. Know that hard acids prefer hard bases and soft acids prefer soft bases; softer acids prefer softer bases.

12) Know that hard-hard interactions tend to be stabilized by strong ionic forces while soft-soft interactions are stabilized by covalent bonds. Be able to explain why this is the case.

13) Be able to use HSAB to explain why heavy metals are toxic.

14) Be able to explain why beryllium is toxic.

15) Be able to use HSAB to explain how chelation therapy works.

16) Be able to name coordination compounds using both the Stock and Ewens-Bassett nomenclature systems.

17) Given the name of a coordination compound be able to write its formula.

18) Know what assumptions crystal field theory makes.

19 Know and understand the crystal field splitting patters for octahedral, tetragonally distorted octahedral, square planar and tetrahedral fields.

20) Know that D_t = 4/9D_o, for a given ligand and metal ion.

21) Understand how the magnitudes of D and P effect the order in which orbitals are filled.

22) Be able to write the electron configurations for both a strong-field (low-spin) case and a weak-field (high-spin) case for a given metal ion or d electron count.

23) Be able to calculate the crystal field stabilization energies in terms of D and P.

24) Understand the factors that affect crystal field splitting energies.

25) Know how to use the spectrochemical series. (don’t need to memorize).

26) Know the two types of metal-ligand p-bonding.

27) Understand how crystal field splitting is related to the color of the coordination complex.

28) Be able to define the following terms: molar susceptibility, diamagnetism, paramagnetism and spin-only magnetic moment.

29) Be able to calculate the spin-only magnetic moment.

30) Be able to write the chemical equations and equilibrium constant expressions for the stepwise formation of a coordination complex.

31) Be able to write the chemical equations and equilibrium constant expressions for the overall formation of coordination complex.